Research Team

“Our team of scientists is not concerned with individual credit, but instead they’re all focused on the ultimate goal.”

David M. Harlan, MD,
Director, JDRF Center of Excellence in New England

It’s now possible to create highly functional insulin-producing beta cells in a lab. These stem cell-derived islets (SC-islets) produce insulin and restore the body’s ability to respond to changes in blood glucose.

Our Goal

Figuring out how to protect transplanted SC-islets from immune destruction, eliminating the need for toxic immunosuppressive therapy. Our research team is working to solve that problem as a cure for Type 1 diabetes.

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Humanized Mouse Core & Diabetes Center of Excellence
UMass Chan Medical School

Clinical, Behavioral and Outcomes Research
Joslin Diabetes Center 

Co-Director, UMass Diabetes Center of Excellence
UMass Chan Medical School

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Co-Director, UMass Diabetes Center of Excellence
UMass Chan Medical School

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Diabetes Center of Excellence
UMass Chan Medical School

Diabetes Center of Excellence
UMass Chan Medical School

Hepatology and Nutrition
Boston Children’s Hospital

Diabetes Center of Excellence
UMass Chan Medical School

Diabetes Center of Excellence
UMass Chan Medical School

Humanized Mice Development
The Jackson Laboratory

Boston Children’s Hospital &
Harvard Stem Cell Institute

Molecular Biotechnology
UMass Chan Medical School

Diabetes Center of Excellence
UMass Chan Medical School

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CRISPR Screen Core
Joslin Diabetes Center